The North American VtES Championship 2010 will be part of White Wolf's Gala Grand Masquerade event, that will take place in New Orleans, Louisiana. The event is scheduled for September 23rd to 26th, 2010. It not only includes the Last Chance Qualifier and the actual North American Championship (Day 1 and 2) for VtES, but also other events like those of the White Wolf's Mind's Eye Theatre LARP and other World of Darkness related events.
You can register yourself and find more information on the The Grand Masquerade website. Beside the registration you can also find information on the event venue, the Roosevelt New Orleans, for which White Wolf offers discounted room rates for the event attendees.